The things described in this article are still happening, so it may be subject to frequent change.
- 1 October - Barb turns 79.
- 2 October - Chris records a reaction video to the fifth part of TF2 Analysis's Red Vs Blue brony cartoon.
- 2 October - Chris informs Ben Saint that he did not curse Donald Trump with COVID-19, and claims that he will not die from the disease.
- 8 October - Chris officially endorses Democratic Party nominees Joe Biden and Kamala Harris for President and Vice President.
- 9 October - Chris tweets out the cover artwork for the incomplete Sonichu 17 comic.
- 16 October - Photos of Chris posing with a group of people known as Praetor are discovered on Instagram.
- 18 October - Country Cookin closes all of its locations due to the financial fallout of the COVID-19 pandemic.
- 26 October - Chris answers more questions on Discord.
- 31 October - Halloween.